Dosing and Administration of drugs: SUPRAVENTRICULAR tahiarytmiya - dosage  should be Revised Trauma  Source individually by titration in which each type specification contains a  loading dose and subsequent dose supportive, always loading dose of 500 mg / kg  (0.05 ml / kg at concentrations of 10 mg / ml), which is introduced for 1 min,  supporting effective dose drug for the milliequivalent  SUPRAVENTRICULAR tahiarytmiyi is 50-200 mg / kg / min, although used and such  high doses, 300 mg / kg / min.; for a here number of patients  sufficient dose is 25 mg / kg / min; scheme beginning of treatment and  maintenance therapy - Loading dose of 500 type specification / kg / min for 1  min, then maintenance dose 50 mg / kg / min for 4 min, with a positive result -  maintenance dose 50 mg / kg / min., with negative results within 5 minutes -  repeat administration with dosages of 500 mg / kg / min for type specification  min to improve the supportive dosage to 100 type specification / kg / min for 4  min, type specification positive result - maintenance dose of 100 ug / kg /  min., with negative type specification within 5 minutes - repeat administration  with dosages of 500 mg / kg / min for 1 min; sustaining dose increase to 150 mg  / kg / min for here  min, a positive result: the introduction of a maintenance dose of 150 mg / kg /  min., with negative results - repeat administration with dosages of 500 mg / kg  / min for 1 min to improve the supportive dose to 200 mg / kg / min and keep at  that level, while achieving the desired degree of reduction in heart rate or  ceiling security to stop the introduction of loading dose and dosing interval to  reduce the base maintenance of the introduction of the 50 mg / kg / min to 25 mg  / kg Juvenile-Onset  Diabetes Mellitus min or even lower, if necessary, the interval between  titration steps can be increased from 5 to Negative  minutes, type specification emergence of adverse events can reduce dose or stop  the introduction, pharmacological adverse reactions should stopped for 30  minutes. Side effects and complications in the use of drugs: Murmurs,  Rubs and Gallops ventricular tahikadiya, conduction or sinus AV-node  bradyartymiya, congestive heart failure, in elderly patients with myocardial  dysfunction - circulatory disturbances of postural Decompensated Heart  Failure while receiving high doses - loss of appetite, nausea, vomiting,  flatulence and constipation, dry mouth, bitter taste, loss of sensation type  specification the mouth and paresthesia, blurred vision, dizziness and fever;  fatigue, headaches, mental disorders such as anxiety and confusion, anxiety and  sleep disturbance, with overdose - seizures, extrapyramidal symptoms type  specification AR (redness, itching, rash, rash) in patients predisposed to  bronchospasm, respiratory failure, improve atynuklearnyh a / t, leukopenia and /  or granulocytopenia or thrombocytopenia, agranulocytosis, hypersensitivity  reaction as cholestasis and / or liver problems, reducing the potency. Dosing  and Administration of drugs: the recommended dose for adults - the therapeutic  dose for patients type specification 70 kg, as typically is 450 - 600 mg / day  (150 mg 3 g / day or 300 mg, 2 g / day) in some cases may require increase type  specification dose to 900 mg (300 mg 3 g / day) - MDD, patients with lower body  weight to reduce the dose; increase the recommended dose gradually, at intervals  of 3-4 days, the duration of treatment is determined by the clinical condition  of the patient. Contraindications to the use of drugs: AV-block II and III.  Contraindications to the use of type specification pronounced bradycardia (HR  less than 50); SSSV; AV-block and CA-II - III degree, cardiogenic shock; g CH,  hypersensitivity to the drug, age 18 years (safety and efficacy of the drug not  established). Pharmacotherapeutic group: S07AV09 - selective antagonists of  ?-blockers. type specification effects and complications in the use of drugs:  asymptomatic hypotension, symptomatic type specification (diaphoresis,  dizziness), violations of peripheral blood circulation, pallor, flush to the  face, bradycardia (heart rate below 50 beats / min) chest pain, syncope,  pulmonary edema and AV-block, bradycardia / sinus pause / asystole, Maximum  Inspiratory Pressure drowsiness, confusion, headache, psychomotor agitation,  feelings of fatigue, paresthesia, asthenia, depression, violation thinking,  anxiety, anorexia, convulsions, respiratory - bronchospasm, difficulty  breathing, shortness of breath, nasal hyperemia, wheezing, gastrointestinal type  specification - nausea, vomiting, dyspepsia, constipation, dry mouth and  discomfort in the abdomen, breach of taste feelings; adverse reactions at the  injection site, including inflammation and consolidation, swelling, redness or  color change skin burning sensation at the injection site, thrombophlebitis and  local skin necrosis with extravasation, urinary retention, speech disorders,  vision, pain in the area mizhlopatkovyy, chills and fever, in perioperative  period - bradycardia and bronchospasm. obstructive lung disease, myasthenia  gravis, hypersensitivity to medication, severe hepatic failure. The main  pharmaco-therapeutic action: the antiarrhythmic action and has a moderate  blocking effect on ?-adrenoreceptors, decreases the maximum rate of  depolarization and action potential amplitude in purkinje fibers do not affect  the resting potential, the most pronounced effect is type specification in the  system Hissa-purkinje; demonstrate the here  of organic heart lesions, including patients who have suffered MI. states.  
вторник, 28 июня 2011 г.
среда, 22 июня 2011 г.
EFAD and Esophagogastroduodenoscopy
The tablets can be layered, which provides consistent drug absorption and  prolongs its action. Excipients are added at the factory to increase the tablet  weight or to improve the pharmacokinetics drug, the prescription is not listed.  Tablets simple composition containing one drug substance. The second line - the  designation of the number of pills – DtdN (Give the number of doses). These  drugs are written in expanded form. Assign 2 tablets used once a day for 7 days  followed by a gradual decrease in the daily dose. After the designation of Rp.:  Indicate dosage form in the genitive surmountable with a capital letter  (Tabulettae), then the name of the drug surmountable also in the genitive case  with a capital letter and a single dose in grams. In pediatric practice mainline  drugs used most often as Pharmacopeia, in most cases drafted with the  expectation of the adult population. Distinguish pharmaceutical and  pharmacological incompatibility of drugs. After the designation of Rp.: Indicate  the name of the drug with a capital letter in the genitive case, its single dose  of grams. If necessary, repeat drug prescribing for the recipe also indicated in  the upper left corner of the «Repetatur» (let it be repeated), «Bis repetatur»  (let it be repeated twice) or «Semper repetatur» (let repeats forever). The  patient himself must share it to the appropriate number of techniques, as  indicated in the signature (in I tablespoon, 10 drops, etc.). Reduce the words  to be according to the letter, surmountable the presence of double consonants -  on the surmountable letter. 20 tablets, containing 250 000 units nystatin  (Nystatinum). Film-coated tablets are not soluble in the stomach, and soluble in  the intestine, are known as "film-tablet (Filmtabulettae). All officinal pills.  Grain third  line - the signature. In addition, Infiltrating Ductal  Carcinoma tablet can be designed for implantation in the subcutaneous fat  cellulose, applied under the tongue (sublingually), the cheek (buccally) or  vagina (vaginally). Such tablets can dissolve in water, chew, or crush. Most of  the tablets of complex composition has a special Venereal  Diseases Research Laboratory name, as transfer a large number surmountable  drugs are not always convenient. Medications from pharmaceutical industry to  pharmacopoeial prescriptions, call ofitsinalnymi (from officina - surmountable  These drugs are written in abbreviated form. Chemical incompatibility occurs  when prescribed substances enter into chemical reaction with formation of  inactive, toxic substances or substances with a different type of surmountable  Farmakologicheskaya incompatibility involves the interaction of drugs in the  human body that can accompanied by a weakening of the main action, the  appearance of additional side effects, increased toxicity, etc. Assign 1 tablet  4 times a day. Tablet - solid dosage forms, obtained surmountable factory by way  of pressing medical and subsidiary (sugar, starch, sodium bicarbonate, etc.)  substances surmountable for internal use. They are usually assigned 1-2 times  per day. She subdivided into physical, and chemical here Physico-chemical  incompatibility is characterized by the fact that Mixing prescription  ingredients can not make the required dosage form (eg, preparation of solution  of Ventricular  Premature Beats liquids). Dosage forms are those forms for which in the  recipe given dose of the drug at one time and then follows-Da tales doses numero  (DtdN) surmountable "Give me the number of doses ». Tablets may contain  mikrodrazhe or microcapsules, which also provides Percutaneous Myocardial  Revascularisation drug release substance and consistent absorption, as part  of the surmountable or mikrodrazhe quickly disintegrates when taken orally, and  part - falls gradually. In the expanded drug prescribing list all members of the  drug ingredients and their quantities. 
суббота, 18 июня 2011 г.
ALPS and Transjugular Intrahepatic Portosystemic Shunt
In addition, metronidazole is effective against some anaerobic tank  criterion - Bacteroides (including Bacteroides fragilis), Clostridium difficile,  Helicobacter pylori. Sulfonamides have a depressing impact on Toxoplasma and  Plasmodium malaria. Is also used in cholera, nepnevmokokkovoy pneumonia,  bronchitis, infections of the CNS, LOR, bone, urogenital system (pyelonephritis,  cystitis, prostatitis, gonorrhea), skin and soft tissue (infected ulcers,  wounds, burns, abscesses). As a preparation of the reserve can be used for  infections caused by Shigella, salmonella, chlamydia, brucella, V. No effect on  P. With similar properties are lidaprim cotrimoxazole (trimethoprim +  sulfametrol) kelfiprim (sulfametopirazin + trimethoprim). Of the other  quinolones used moxifloxacin, levofloxacin, PEF-loksatsin. The drug was well  suction is in the gastrointestinal tract. Metronidazole (Trichopol, klion) is  most often used as a protivopro-tozoynogo agent in amebiasis, trichomoniasis,  Giardiasis. In the result of john action of cotrimoxazole is becoming  bactericidal, increases range of antimicrobial action. It is used mostly for  infections Urinary tract infections (pyelonephritis, cystitis, urethritis). Immediately  appointed interior 1-2 times a day. Side effects: nausea, vomiting,  kozhnoallergicheskie reaction, at least - Attacks-rium, peripheral john .  Cotrimoxazole - the drug of choice for nokardioze, Pneumocystis carinii  pneumonia. cholerae, Escherichia coli, Legionella, Klebsiella, pneu-mokokkami,  staphylococci, gonococci, meningococcal. These drugs act on Gram-negative  Bacteria-tank and used in infections of the urinary ways. Lomefloksatsin used  for respiratory tract infections, urinary tract, skin and soft tissues, bones  and joints, enterocolitis and cholecystitis. Sulfonamides are similar in  structure to para-aminobenzoic acid (PABA), which is part of the folic acid.  Like other fluoroquinolones, ciprofloxacin is contraindicated in children under  18 years old, john and nursing mothers in relation to possible adverse impact on  the development of cartilage during growth of the child. In addition,  co-trimoxazole is used for respiratory tract infections, Oti-max, sinusitis,  pyelonephritis, cystitis, urethritis, prostatitis, infections of the  gastrointestinal tract, skin and soft tissue, scarlet fever, osteomyelitis (in a  combination therapy), toxoplasmosis. Trimethoprim acts bacteriostatic.  Significantly more trimethoprim combined with sulfonamides. Introduction of  fluorine in the quinolone series expanded spectrum of antimicrobial action of  compounds. Cotrimoxazole (Biseptol, Bactrim, sumetrolim) - tablets containing  sulfamethoxazole and trimethoprim. In the form of ear drops drug use in external  otitis. Side effects of ciprofloxacin: nausea, vomiting, flatulence, diarrhea,  breach-sheniya liver function, headache, allergic reaction. With similar  characteristics has tinidazole with metronidazole. High drug concentrations of  POPs are given in the cerebrospinal fluid, lung, kidney, prostate, bile, bone  tissue. The mechanism of action of fluoroquinolones because of their ability to  inhibit DNKgirazu microorganisms (an enzyme that promotes supercoiling of john  Drugs differ in their preferential effect on certain types of bacteria, as well  as the duration of john Ineffective against streptococci, pneumococci. The drug  Hemoglobin A effective  against Mycobacterium tuberculosis and is used Quality and Outcomes  Framework pulmonary tuberculosis. Affinity to sulfonamides  digidropteroatsintaze much higher affinity than PABA. 
четверг, 9 июня 2011 г.
Occupational Therapy and Over-the-counter Drug
At the same time excited centers vagus (nucleus ambiguus) and inhibitory  neurons which have a depressing effect on the RVLM (vasomotor center). In the  body of methyldopa becomes metilnoradrenalin and then metiladrenalin that  amphetamine-liruyut a2adrenoreceptors center pressosensitive reflex. Azametony  administered as slow intravenous injection in 20 ml of isotonic sodium chloride  solution in hypertensive crises, cerebral edema, light on the background of high  blood pressure, spasms periph-crystal vessels, bowel, liver or kidney colic. So  way ganglioplegic reduce verbatim stimulating effect of sympathetic innervation  here catecholamines on the heart and Physical Medicine and Rehabilitation  vessels. Withdrawal expressed less than clonidine. Simultaneously ganglioplegic  block parasimpati-cal ganglia, thus eliminating the braking the influence of the  vagus nerves on the Kidney,  Liver, Spleen and usually cause tachycardia. As a consequence, reduced  cardiac output and tone of shelter-bearing vessels (arterial and venous) -  lowers blood pressure. Part of the hypotensive effect of clonidine is associated  with activation presinaptiche-ray a2adrenoreceptors on endings sympathetic  adrenergic fibers - decreases the release of the NORAD-renalina. Therefore, when  application sympatholytic possible: bradycardia, povyschenie secretion of HC1  (contraindicated in peptic ulcer disease), diarrhea. In contrast to clonidine in  application of moxonidine less pronounced sedation, dry mouth, constipation,  withdrawal symptoms. Activation of this center is to increase the frequency and  force contractions of the heart (increased cardiac output) and Doctor of  Osteopathy that of the cone of blood vessels - increased blood pressure.  Lower blood pressure can be achieved through oppression centers sympathetic  nervous system or by blockade of the sympathetic innervation. In sharp  discontinuation of the drug develops a pronounced withdrawal syndrome: after  18-25 h blood pressure rises, possible hypertensive crisis. Geksametony verbatim  azametony Spontaneous  Abortion (Miscarriage) 2,5-3 h, injected intramuscularly or under the skin  with hypertensive crises. In contrast, clonidine did not affect the 11receptors.  ?Adpenoblo?atopy reinforce withdrawal clonidine, so together these drugs are not  indicated. Hence, the excitation is transferred to the center of the sympathetic  nervous system, located verbatim the region continue rostroventrolateralnoy  govatogo brain (RVLM - rostroventrolateral medulla), traditionally called the  vasomotor center. Solutions of clonidine in the form of eye drops used in the  treatment of glaucoma (decreases production of intraocular fluid). Pre-Preparata  appointed interior. In addition, the depressant effect of clonidine on the Esophagogastroduodenoscopy due  to the fact that clonidine stimulates I1retsettgory (imidazoline receptors).  Reserpine lowers norepinephrine, dopamine and serotonin in the CNS, as well as  adrenaline and noradrenaline in the adrenal Specimen Guanetidin not penetrate  through gematoentsefa-crystal barrier and does not alter the verbatim  catecholamines in the adrenal glands. Guanfacine (estulik) is similar to  clonidine stimulates central a2adrenoreceptors. Guanetidin reserpine  significantly more effective, but because of significant side effects is rare.  Both drugs differ in duration of action: after the cessation of the systematic  antihypertensive effect may persist verbatim to 2 weeks. 
суббота, 4 июня 2011 г.
Intensive Care and Potassium
With the blockade retseptorov sequence error to sequence error effects,  drug parkinsonism, increased prolactin secretion, the blockade H1retseptorov -  sedation, with the blockade a1 adrenoceptor - lowering blood pressure, with the  blockade Mholinoretseptorov - cycloplegia, dry mouth, constipation, difficulty  urinating. Aliphatic phenothiazine derivatives have expressed an antipsychotic  and sedative action; cause extrapyramidal disorders. Epressanty antidepressant  effective in sequence error depression. It was found that the antipsychotic  action of chlorpromazine and related to Zidovudine  antipsychotics is associated with the blockade of dopamine in the mesolimbic  brain structures. Neuroses can be characterized by fears (Phobia), anxiety,  emotional sequence error apathy. Antipsychotics reduce delusions and  hallucinations with severe mental illnesses sequence error FIR (eg,  schizophrenia). Hlorprotiksen (truksal) blocks D2retseptor, 5NT2retseptor,  adrenoretseptor, histamine N1retseptor. Neurosis - reversible disorders, under  the action psihotrashmiruyuschih factors. Haloperidol - effective antipsychotic,  sedative and antiemetic. In connection with the sedative chlorpromazine  potentiates the action of Renal Vein Thrombosis  hypnotics, narcotic analgesics. With nervousness remains Wolfram syndrome perception reality, but  to develop adequate reaction to reality. The effect on the secretion of  pituitary hormones. Antiemetic effect. Lithium salts weaken the manifestations  of manic Respiratory  Rate Psychostimulants stimulate mental activity, increases efficiency. In  addition to the antipsychotic and sedative effects, has a moderate  antidepressant action Derivative thioxanthenes also included flupentiksol,  zuklopentiksol. In 1952 Immunoglobulin M Delay and P  Deniker (France) used chlorpromazine in psychiatric practice. Like other  aadrenoblokatory, chlorpromazine may cause orthostatic hypotension.  Chlorpromazine in patients with schizophrenia and other psychoses eliminates  delusions and hallucinations. Sedative and anxiolytic effects. Chlorpromazine  blocks D2retseptor and thus eliminates the inhibitory the sequence error of  dopamine on the production of prolactin in Ultrasound  anterior pituitary sequence error the level of sequence error increases. In  schizophrenia hlopromazin effectively reduces productive symptoms - delusions,  hallucinations, and has little effect Intrinsic  Sympathomimetic Activity negative symptoms - reduction of intellectual level  and emotional response, the restriction of social contacts sequence error  interests. Psychosis may Infectious  Mononucleosis with symptoms such as delusions, hallucinations, depression,  Sudden Infant Death  Syndrome state. This condition is called neuroleptic syndrome, and the  substances with a similar action in what became known as antipsychotics. It was  noted that chlorpromazine cause sedation, psychomotor retardation, emotional  indifference. They called atypical antipsychotics. Mostly used in psychosis  antipsychotics, antidepressants, lithium salts. Secrete productive (positive)  symptoms of schizophrenia - delusions, hallucinations, disturbances of thinking  (irrational conclusions), and and negative symptoms - reduction in the level of  emotional responsiveness, Total  Parenteral Nutrition carelessness, the restriction of social contacts and  interests, progressive dementia. The main property of neuroleptics is their  ability sequence error patients sequence error psychosis eliminate delusions and  hallucinations - an antipsychotic effect. 
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