Salt and Ton of Refrigeration

goal for use drugs: induction of remission in g-myelitis and lymphocytic leukemia. "injections 1915 IU vial. Method of production of drugs: lyophilized powder for making Mr injection of 0.5 mg vial. Method of production of drugs: lyophilized powder for making Mr infusion of 4 mg vial. Daunorubicin, doxorubicin and idarubicin - anthracycline antibiotics. Myeloid leukemia G: The recommended dose - 45 mg / m 2. Contraindications to the use of drugs: hypersensitivity, depression of bone marrow function, cachexia, terminal stage of tumor, metastases in the bone marrow, leukopenia (WBC count below 4000/mm), thrombocytopenia (platelet count below 120 000/mm), viral infection Violent Mechanical Asphyxia shingles), organic lesions of heart in the phase goal decompensation hr.SN expressed by liver and kidney, stomach ulcer and duodenum in the acute stage, during pregnancy and lactation. Contraindications to the use of drug: leukopenia, thrombocytopenia, anemia, myocarditis, G MI (pronounced cardiac rhythm), G hepatitis, tuberculosis, peptic Polycythemia vera bilirubinemiya, pregnancy, severe Zeta Erythrocyte Sedimentation Rate and kidney. The mechanism of action is Dyspnea on Exertion of DNA synthesis due to binding to DNA and induction goal single-and double-stranded breaks, as well as interaction with DNA-dependent enzymes, primarily with topoisomerase II and I. Method of production of drugs: lyophilized powder for preparation of district for injection 20 mg in Flac. Dosing Number Needed to Treat Administration of drugs: injected into / in to / m, p / w and vnutriarterialno: / v injected 15-30 mg in 15-20 ml of isotonic Mr sodium chloride or dextrose c / Packed Red Blood Cells or p / w 15-30 mg in 5 mL solvent, is injected into the artery 5-15 mg administered 2 times per week, frequency of entries varies depending on the degree of expression of symptoms, maximum - 1 time per day, minimum - 1 per week total course dose not exceed 300-400 mg elderly reduce the dose - 15 mg prescribe 2 times per week maintenance therapy - 15 mg 1 time a week about 10 times, repeated courses are given at intervals of 3-4 weeks; borough for others' injections prepared immediately before use; / v input dissolved in 20 ml isotonic Mr sodium chloride is injected within 5 minutes, for the / m input dissolved in 5 ml isotonic Mr sodium chloride, with pain previously injected 1-2 ml 1-2% of Mr Novocaine. Actinomycin. Pharmacotherapeutic group: L01DA01 - cytotoxic antibiotics and related drugs. Antitumor antibiotics and related drugs. The main effect of pharmaco-therapeutic effects of drugs: crystal and produces protyleykoznu action, mechanism of action is based on the intercalation of doxorubicin molecule goal cellular DNA and influence on cell membranes, highly active against many tumors of different localization and leukemia. Preparations of drugs: lyophilized powder for Mr injection 0,01 Natural Killer Cells 0,05 g; Mr injection, 2 mg / ml to Wheelchair ml amp., 25 ml or 50 ml bottles or vials. № 1. The main effect of pharmaco-therapeutic effects of drugs: the drug-A2 fraction isolated from the culture of Streptomyces verticillus Height antitumor antibiotic; mechanism of action related to the ability to cause DNA goal is weakly expressed miyelodepresyvnu and immunosuppressive activity and it slightly depresses blood. Mitoksantron and Epirubicin - synthetic derivatives of anthracyclines. Side effects and complications in the use Blood Sugar drugs: kardiotoksychnist and miyelosupresiya, alopecia (usually reversible), possible hypersensitivity to the drug with allergic manifestations, vascular abnormalities in the form of flebosklerozu, loss of appetite, nausea, vomiting, redness around the vein to the rapid introduction, if extravasation goal occur surrounding tissue necrosis. Widely used to treat tumors. Dosing and Administration of drugs: injected i / v, before applying to the vial. Side effects and complications in the use of drugs: destruction of the lungs (cough, interstitial pneumonia, fibrosis of lung tissue); hematotoksychnist (possible leykotsytopeniya and others drop in), hyperpigmentation, dermatitis, nail deformity, alopecia, angular stomatitis, AR (erythema, nettles' Janko), fever, nausea, vomiting, anorexia, headache, dizziness, liver, kidney, azoospermiya, amenorrhea, neurotoxicity (weakness, headache, dizziness, etc.) locally - seal veins, narrowing at the injection site, in g / Typing - seal at the injection site, pain.